single oropharyngeal sample was obtained from each subject in a standardized manner questionnaire, procedure

INSTRUCTIONS TO CANDIDATES

ANSWER ALL QUESTIONS

1   Description of the assignment

1.1  Description of the data file:

From January 18 to August 29 2017, consecutive children who had received the 4-dose course of PCV13, as per the National Immunization Program recommendations, were prospectively enrolled through 45 general pediatric practice facilities in 30 municipalities in Greece. A single oropharyngeal sample was obtained from each subject in a standardized manner (questionnaire, procedure).

Based on the time interval since the fourth dose of PCV13, the children sampled were grouped for analysis in 6 groups: 26 days to 11 months (m); 12-23 m; 24-35 m; 36-47 m; 48-59 m and 60-71 m. (column E).

Carriage and distribution of Streptococcus pneumoniae serotypes was detected by RT-PCR (Column J to N). Blank cells

Demographics (Columns B and C)

Confounding factors (Columns F and I)

 

1.2        Objective of the program

 

Create 7 different files with results as the attached list of rtf files. Macros should be used (or any other programing approach) to perform repeated tasks

File	Description	SAS procedure
1	Demographics by total colonization including table footnotes	Customized program, choose your own approach
2	table of distributions of confounders and Grouping and graphs	Proc tabulate and proc gplot
3	Logistic regression where Grouping is an ordinal variable (1, 2, 3, 5, 6) for column J   Rows with confounders missing are excluded	proc logistic data=XX;    class XX  (param=ref);       model XX (event=' XX ')= XX / scale=none                             clparm=wald                             clodds=pl                             rsquare;  where XX ne ' XX ';    run;
4	Logistic regression where Grouping is an ordinal variable (1, 2, 3, 5, 6) for column K   Rows with confounders missing are excluded	As above
5	Logistic regression where Grouping is an ordinal variable (1, 2, 3, 5, 6) for column L   Rows with confounders missing are excluded	As above
6	Logistic regression where Grouping is an ordinal variable (1, 2, 3, 5, 6) for column M   Rows with confounders missing are excluded	As above
7	Logistic regression where Grouping is an ordinal variable (1, 2, 3, 5, 6) for column N   Rows with confounders missing are excluded.	As above

 

Attachments:

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